The introduction of high-throughput DNA sequencing has led to the generation of large quantities of genomic sequencing data that have to be stored, transferred and analyzed. So far WG 11 (MPEG) and ISO TC 276/WG 5 have addressed the representation, compression and transport of genome sequencing data by developing the ISO/IEC 23092 standard series also known as MPEG-G. They provide a file and transport format, compression technology, metadata specifications, protection support, and standard APIs for the access of sequencing data in the native compressed format.

An important element in the effective usage of sequencing data is the association of the data with the results of the analysis and annotations that are generated by processing pipelines and analysts. At the moment such association happens as a separate step, standard and effective ways of linking data and meta information derived from sequencing data are not available.

At its 127th meeting, MPEG and ISO TC 276/WG 5 issued a joint Call for Proposals (CfP) addressing the solution of such problem. The call seeks submissions of technologies that can provide efficient representation and compression solutions for the processing of genomic annotation data.

Companies and organizations are invited to submit proposals in response to this call. Responses are expected to be submitted by the 8th January 2020 and will be evaluated during the 129th WG 11 (MPEG) meeting. Detailed information, including how to respond to the call for proposals, the requirements that have to be considered, and the test data to be used, is reported in the documents N18648, N18647, and N18649 available online. For any further question about the call, test conditions, required software or test sequences please contact: Joern Ostermann, MPEG Requirements Group Chair ( or Martin Golebiewski, Convenor ISO TC 276/WG 5 (